Optimization of Coenzyme Q₁₀Production Procedure from Genetic Engineered Rhodobacter sphaeroides Overexpressing UbiG

更新时间:2023-05-28

【摘要】In the present study, single factors including fermentation temperature, inoculate amount, fermentation duration, and ratio of fermentation medium volume to total flask volume（dissolved oxygen tension） were optimized for enhancing the production of coenzyme Q10 from genetic engineered Rhodobacter sphaeroides overexpressing UbiG. The experimental results suggested that optimal single factors were: inoculate amount 2%, fermentation temperature 30 ℃, fermentation duration 48 h, and ratio of fermentation medium volume to total flask volume 80%. The present study will promote the large scale production of CoQ10 from microorganisms.

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